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Vitiligo ( / ˌvɪtɪˈlaɪɡoʊ /) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [5] [6] Treatment options include topical medications, light therapy, surgery and cosmetics.
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system —the organ system that encloses the body and includes skin, nails, and related muscle and glands. [1] The major function of this system is as a barrier against the external environment. [2]
The condition is the most severe form of ichthyosis (except for syndromes that include ichthyosis, for example, Neu–Laxova syndrome), a group of genetic disorders characterised by scaly skin. [8] Harlequin-type ichthyosis is caused by mutations in the ABCA12 gene . [4]
Schamberg's disease, or progressive pigmented purpuric dermatosis, is a chronic discoloration of the skin which usually affects the legs and often spreads slowly. This disease is more common in males and may occur at any age from childhood onward. This condition is observed worldwide and has nothing to do with race or ethnic background.
Darier's disease. Darier's disease (DAR) is a rare, inherited skin disorder that presents with multiple greasy, crusting, thick brown bumps that merge into patches. [4] It is an autosomal dominant disorder discovered by French dermatologist Ferdinand-Jean Darier . Mild forms of the disease are the most common, consisting solely of skin rashes ...
Hailey–Hailey disease (HHD), or familial benign chronic pemphigus: 559 or familial benign pemphigus,: 622 was originally described by the Hailey brothers (Hugh Edward and William Howard) in 1939. [3] [4] It is a genetic disorder that causes blisters to form on the skin.
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [4] [5] These areas are red, pink, or purple, dry, itchy, and scaly. [8] [3] Psoriasis varies in severity from small localized patches to complete body coverage. [3] Injury to the skin can trigger psoriatic skin changes at that spot, which ...
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