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Hypodiploid acute lymphoblastic leukemia. Hypodiploid acute lymphoblastic leukemia is the chromosome mutation of leukemic cells with 45 chromosomes or less. It has been determined that the prognosis of hypodiploid is much worse than standard acute lymphoblastic leukemia. [1] The lower the chromosome count, the lower the survival rate.
Lymphoblast. A lymphoblast is a modified naive lymphocyte with altered cell morphology. It occurs when the lymphocyte is activated by an antigen and increased in volume by nucleus and cytoplasm growth as well as new mRNA and protein synthesis. The lymphoblast then starts dividing two to four times every 24 hours for three to five days, with a ...
T-cell leukemia describes several different types of lymphoid leukemias which affect T cells. [citation needed] The most common T-cell leukemia is precursor T-cell lymphoblastic leukemia. It causes 15% of acute leukemias in childhood, and also 40% of lymphomas in childhood. It is most common in adolescent males.
Asparaginase is an enzyme that is used as a medication and in food manufacturing. [6] [7] As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL). [6] It is given by injection into a vein, muscle, or under the skin. [6]
Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center. It is named after Denis Parsons Burkitt , the Irish surgeon who first described the disease in 1958 while working in equatorial Africa .
Mixed-phenotype acute leukemia. Mixed-phenotype acute leukemia ( MPAL) is a group of blood cancers ( leukemia) which have combined features of myeloid and lymphoid cancers. It is a rare disease, constituting about 2–5% of all leukemia cases. [1] It mostly involve myeloid with either of T lymphocyte or B lymphocyte progenitors, but in rare ...
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