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Schamberg's disease is a skin disorder that causes a discoloration of the lower extremities. It usually occurs in the lower extremities and rarely elsewhere. This condition is caused by leaky blood vessels near the surface of the skin. The cause of the leaky capillaries is usually not known.
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.
Prurigo nodularis (PN), also known as nodular prurigo, is a skin disorder characterized by pruritic , nodular lesions, which commonly appear on the trunk, arms and legs. Patients often present with multiple excoriated nodules caused by chronic scratching.
Darier's disease (DAR) is a rare, inherited skin disorder that presents with multiple greasy, crusting, thick brown bumps that merge into patches. It is an autosomal dominant disorder discovered by French dermatologist Ferdinand-Jean Darier .
Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure.
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands.