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The major focus of Weiner's career has been the study of MS, which he began in 1972 as a resident in neurology at the Peter Bent Brigham Hospital in Boston. More recently he has studied immune mechanisms in other neurologic diseases including Alzheimer's disease and ALS.
Stephen L. Hauser is a professor of the Department of Neurology at the University of California, San Francisco (UCSF) specializing in immune mechanisms and multiple sclerosis (MS). He has contributed to the establishment of consortia that have identified more than 50 gene variants that contribute to MS risk. [1]
Multiple sclerosis is an autoimmune disease, primarily mediated by T-cells. The three main characteristics of MS are the formation of lesions in the central nervous system (also called plaques), inflammation, and the destruction of myelin sheaths of neurons.
Fred D. Lublin is an American neurologist and an authority on the treatment of multiple sclerosis. Along with colleagues at the National Multiple Sclerosis Society , his work redefined the clinical course definitions of MS. [1]
Aaron E. Miller is an American neurologist, the first Chairman of the Multiple Sclerosis section of the American Academy of Neurology (AAN) and recognized as a multiple sclerosis clinician. [1] [2] Miller is both a professor of neurology at the Icahn School of Medicine at Mount Sinai and medical director of the Corinne Goldsmith Dickinson ...
The McDonald criteria facilitate the diagnosis of MS in patients who present with their first demyelinating attack and significantly increase the sensitivity for diagnosing MS without compromising the specificity.
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