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30,000 (2015) [ 4 ] Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [ 1 ] It typically results in warm, swollen, and painful joints. [ 1 ] Pain and stiffness often worsen following rest. [ 1 ] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the ...
Gene therapy for osteoarthritis. Gene therapy for osteoarthritis is the application of gene therapy to treat osteoarthritis (OA). Unlike pharmacological treatments which are administered locally or systemically as a series of interventions, gene therapy aims to establish sustained therapeutic effect after a single, local injection. [1]
Arthritis is a term often used to mean any disorder that affects joints. [2] Symptoms generally include joint pain and stiffness. [2] Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. [2][3] In some types of arthritis, other organs are also affected. [7]
A disease-modifying osteoarthritis drug (DMOAD) is a disease-modifying drug that would inhibit or even reverse the progression of osteoarthritis. [1] Since the main hallmark of osteoarthritis is cartilage loss, a typical DMOAD would prevent the loss of cartilage and potentially regenerate it. Other DMOADs may attempt to help repair adjacent ...
Frequency. 237 million / 3.3% (2015) [4] Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5][6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7] The most common symptoms are joint pain ...
Prolotherapy. Prolotherapy, also called proliferation therapy, is an injection-based treatment used in chronic musculoskeletal conditions. [1] It has been characterised as an alternative medicine practice. [2]
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