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  2. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    Treatment. CLL treatment focuses on controlling the disease and its symptoms rather than on an outright cure. In those without or only minimal symptoms watchful waiting is generally appropriate. CLL is treated by chemotherapy, radiation therapy, biological therapy, or bone marrow transplantation.

  3. Monoclonal B-cell lymphocytosis - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_B-cell_lymphocy...

    Monoclonal B-cell lymphocytosis. Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic condition in which individuals have increased blood levels of particular subtypes of monoclonal lymphocytes (i.e. an aberrant and potentially malignant group of lymphocytes produced by a single ancestral cell). This increase must persist for at least 3 ...

  4. Ofatumumab - Wikipedia

    en.wikipedia.org/wiki/Ofatumumab

    Ofatumumab is a fully human monoclonal antibody to CD20, which appears to provide rapid B-cell depletion. [13] Under the brand name Kesimpta, it is approved for the treatment of multiple sclerosis in the United States as well as in the European Union and other regions. [9] [11] Under the brand name Arzerra, it is approved for the treatment of ...

  5. Chlorambucil - Wikipedia

    en.wikipedia.org/wiki/Chlorambucil

    Chlorambucil, sold under the brand name Leukeran among others, is a chemotherapy medication used to treat chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, and non-Hodgkin lymphoma. For CLL it is a preferred treatment. It is given by mouth. Common side effects include bone marrow suppression.

  6. Richter's transformation - Wikipedia

    en.wikipedia.org/wiki/Richter's_transformation

    Richter's transformation (RT), also known as Richter's syndrome, is the conversion of chronic lymphocytic leukemia (CLL) or its variant, small lymphocytic lymphoma (SLL), into a new and more aggressively malignant disease. [1] CLL is the circulation of malignant B lymphocytes with or without the infiltration of these cells into lymphatic or ...

  7. Alemtuzumab - Wikipedia

    en.wikipedia.org/wiki/Alemtuzumab

    Alemtuzumab. Alemtuzumab, sold under the brand names Campath and Lemtrada among others, is a medication used to treat chronic lymphocytic leukemia and multiple sclerosis. [8] In chronic lymphocytic leukemia, it has been used as both a first line and second line treatment. [8] It is given by injection into a vein.

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