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Multiple sclerosis ( MS) is an autoimmune disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. [3] This damage disrupts the ability of parts of the nervous system to transmit signals, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric problems.
Life expectancy 6–12 years after onset of symptoms. Frequency. 5 per 100,000 people. Multiple system atrophy ( MSA) is a rare neurodegenerative disorder [1] characterized by tremors, slow movement, muscle rigidity, and postural instability (collectively known as parkinsonism ), autonomic dysfunction and ataxia.
Management of multiple sclerosis. Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS). Several therapies for it exist, although there is no known cure. The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable ...
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The major focus of Weiner's career has been the study of MS, which he began in 1972 as a resident in neurology at the Peter Bent Brigham Hospital in Boston. More recently he has studied immune mechanisms in other neurologic diseases including Alzheimer's disease and ALS.
Chronic inflammatory demyelinating polyneuropathy (or polyradiculoneuropathy) is considered an autoimmune disorder destroying myelin, the protective covering of the nerves. Typical early symptoms are "tingling" (sort of electrified vibration or paresthesia) or numbness in the extremities, frequent (night) leg cramps, loss of reflexes (in knees ...
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