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Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. [4] For the prevention of cardiovascular disease, statins are a first-line treatment. [4] It is taken by mouth.
Medical uses. Statins are usually used to lower blood cholesterol levels and reduce risk for illnesses related to atherosclerosis, with a varying degree of effect depending on underlying risk factors and history of cardiovascular disease. [16] Clinical practice guidelines generally recommend people start with lifestyle modification through a ...
The discovery of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related diseases. Hypercholesterolemia is considered to be one of the major risk factors for atherosclerosis which often leads to cardiovascular, cerebrovascular and peripheral vascular ...
Statins help lower cholesterol. For this observational study, researchers analyzed data from the U.K. Biobank and Whitehall II study of more than 20,000 adults in the U.K. 70 years and older with ...
Atorvastatin. Rosuvastatin. You may be prescribed a statin for a short period of time, or be prescribed a statin alongside other treatments or medications. Statin therapy isn’t for everyone, though.
Bruce Roth. Bruce D. Roth is an American organic and medicinal chemist who trained at Saint Joseph's College, Iowa State University and the University of Rochester, and, at the age of 32, discovered atorvastatin, the statin -class drug sold as Lipitor that would become the largest-selling drug in pharmaceutical history (as of 2003).
Red yeast rice [10] is the natural source from which statins were discovered, but the FDA currently disallows any RYR with significant amounts of statin to be sold as a dietary supplement [11] Boswellia serrata [12] L-arginine may enhance the effects of a Statin, but will not lead to a reduction in cholesterol alone. [13] Flaxseed oil [14]
Statins “help reduce the risk of plaque ruptures and stabilize the blood vessels” in addition to reducing cholesterol, Serwer says. These medications are a “first-line therapy, after diet ...