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Sonophoresis also known as phonophoresis, is a method that utilizes ultrasound to enhance the delivery of topical medications through the stratum corneum, to the epidermis and dermis. Sonophoresis allows for the enhancement of the permeability of the skin along with other modalities, such as iontophoresis , to deliver drugs with lesser side ...
Phonophoresis, also known as sonophoresis, is the method of using ultrasound waves to increase skin permeability in order to improve the effectiveness of transdermal drug delivery. This method intersects drug delivery and ultrasound therapy.
Iontophoresis. Iontophoresis is a process of transdermal drug delivery by use of a voltage gradient on the skin. [1] [2] Molecules are transported across the stratum corneum by electrophoresis and electroosmosis and the electric field can also increase the permeability of the skin.
Scrubber systems (e.g. chemical scrubbers, gas scrubbers) are a diverse group of air pollution control devices that can be used to remove some particulates and/or gases from industrial exhaust streams. An early application of a carbon dioxide scrubber was in the submarine the IctÃneo I, in 1859; a role for which they continue to be used today.
Phonophoresis, also known as sonophoresis, is the use of ultrasound to enhance the delivery of topically applied drugs. Home ultrasound allows the application of topically applied analgesics and anti-inflammatory agents through the therapeutic application of ultrasound.
Sonophoresis: Application of an ultrasound at the skin to overcome the skin barrier. Microneedles: Application of micro-sized needles to bypass the stratum corneum for drug delivery, with the intention of decreasing pain and improving patient compliance. Magnetophoresis Application of a magnetic field to increase skin permeability.
The ultrasound can either be low-frequency, or LFUS, (between ~20 and ~100 kHz) or high-frequency, HFUS, (>1 MHz). Transdermal delivery (sonophoresis) is enhanced through LFUS, which then further allows the drug to be released. Since the wave of HFUS is higher, success of drug delivery has been demonstrated through the form of bubbles.
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Sonoporation, or cellular sonication, is the use of sound in the ultrasonic range for increasing the permeability of the cell plasma membrane. This technique is usually used in molecular biology and non-viral gene therapy in order to allow uptake of large molecules such as DNA into the cell, in a cell disruption process called transfection or ...
Analog sound reproduction is the reverse process, with a larger loudspeaker diaphragm causing changes to atmospheric pressure to form acoustic sound waves. Digital recording and reproduction converts the analog sound signal picked up by the microphone to a digital form by the process of sampling.