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This requires them to increase their drug dosage to maintain the benefit, and that in turn also increases the unwanted side effects. Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. All of the opioids can cause side effects.
Metronomic therapy. Metronomic therapy is a new type of chemotherapy in which anti-cancer drugs are administered in a lower dose than the maximum tolerated dose repetitively over a long period to treat cancers with fewer side effects. Metronomic therapy is shown to affect both tumor microenvironment and tumor cells to achieve its therapeutic ...
Scrambler therapy involves the use of electronic stimulation on the skin with the goal of overwhelming pain information with non-pain information. [1] In a therapy session, "electrocardiographic-like pads are placed around the area of pain". [2] There is not much research on the efficacy of scrambler therapy. [3]
Prism adaptation. Prism adaptation is a sensory-motor adaptation that occurs after the visual field has been artificially shifted laterally or vertically. It was first introduced by Hermann von Helmholtz in late 19th-century Germany as supportive evidence for his perceptual learning theory (Helmholtz, 1909/1962). [1]
Prism (optics) An optical prism is a transparent optical element with flat, polished surfaces that are designed to refract light. At least one surface must be angled — elements with two parallel surfaces are not prisms. The most familiar type of optical prism is the triangular prism, which has a triangular base and rectangular sides.
Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]
Image-guided radiation therapy is the process of frequent imaging, during a course of radiation treatment, used to direct the treatment, position the patient, and compare to the pre-therapy imaging from the treatment plan. [1] Immediately prior to, or during, a treatment fraction, the patient is localized in the treatment room in the same ...
Nafamostat is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. [3] The mechanism of action of nafamostat is as a slow tight-binding substrate, trapping the target protein in the acyl-enzyme intermediate form, resulting in apparent observed inhibition. [4] [5]
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