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In statistics, Bessel's correction is the use of n − 1 instead of n in the formula for the sample variance and sample standard deviation, where n is the number of observations in a sample. This method corrects the bias in the estimation of the population variance.
To determine the sample size n required for a confidence interval of width W, with W/2 as the margin of error on each side of the sample mean, the equation Z σ n = W / 2 {\displaystyle {\frac {Z\sigma }{\sqrt {n}}}=W/2} can be solved.
This depends on the sample size n, and is given as follows: c 4 ( n ) = 2 n − 1 Γ ( n 2 ) Γ ( n − 1 2 ) = 1 − 1 4 n − 7 32 n 2 − 19 128 n 3 + O ( n − 4 ) {\displaystyle c_{4}(n)={\sqrt {\frac {2}{n-1}}}{\frac {\Gamma \left({\frac {n}{2}}\right)}{\Gamma \left({\frac {n-1}{2}}\right)}}=1-{\frac {1}{4n}}-{\frac {7}{32n^{2}}}-{\frac ...
Where is the sample size, = / is the fraction of the sample from the population, () is the (squared) finite population correction (FPC), is the unbiassed sample variance, and (¯) is some estimator of the variance of the mean under the sampling design. The issue with the above formula is that it is extremely rare to be able to directly estimate ...
Welch's t-test defines the statistic t by the following formula: t = Δ X ¯ s Δ X ¯ = X ¯ 1 − X ¯ 2 s X ¯ 1 2 + s X ¯ 2 2 {\displaystyle t={\frac {\Delta {\overline {X}}}{s_{\Delta {\bar {X}}}}}={\frac {{\overline {X}}_{1}-{\overline {X}}_{2}}{\sqrt {{s_{{\bar {X}}_{1}}^{2}}+{s_{{\bar {X}}_{2}}^{2}}}}}\,}
For example, in the R statistical computing environment, this value can be obtained as fisher.test(rbind(c(1,9),c(11,3)), alternative="less")$p.value, or in Python, using scipy.stats.fisher_exact(table=[[1,9],[11,3]], alternative="less") (where one receives both the prior odds ratio and the p -value).
This approximate formula is for moderate to large sample sizes; the reference gives the exact formulas for any sample size, and can be applied to heavily autocorrelated time series like Wall Street stock quotes. Moreover, this formula works for positive and negative ρ alike. See also unbiased estimation of standard deviation for more discussion.
With these data, the sample size (161 patients) is not small, however results from the McNemar test and other versions are different. The exact binomial test gives p = 0.053 and McNemar's test with continuity correction gives = 3.68 and p = 0.055.
The effect of Yates's correction is to prevent overestimation of statistical significance for small data. This formula is chiefly used when at least one cell of the table has an expected count smaller than 5. Unfortunately, Yates's correction may tend to overcorrect.
If the sample mean and uncorrected sample variance are defined as X ¯ = 1 n ∑ i = 1 n X i S 2 = 1 n ∑ i = 1 n ( X i − X ¯ ) 2 {\displaystyle {\overline {X}}\,={\frac {1}{n}}\sum _{i=1}^{n}X_{i}\qquad S^{2}={\frac {1}{n}}\sum _{i=1}^{n}{\big (}X_{i}-{\overline {X}}\,{\big )}^{2}\qquad }