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Many of the side effects are due to the hyperosmolar solution being injected. i.e. they deliver more iodine atoms per molecule. The more iodine, the more "dense" the X-ray effect. Organic iodine molecules used for contrast include iohexol , iodixanol , and ioversol .
Iodine (medical use) Iodine is a chemical element with many uses in medicine, depending on the form. Elemental iodine and iodophors are topical antiseptics. [2] Iodine, in non-elemental form, functions as an essential nutrient in human biology (see iodine in biology ). [3] Organic compounds containing iodine are also useful iodinated contrast ...
Relatively common side effects include vomiting, diarrhea, and skin redness. Other side effects include itchiness, kidney problems, low blood pressure, and allergic reactions. It is not recommended in people who have an iodine allergy. Diatrizoate is an iodinated ionic radiocontrast agent with high osmolality.
Adverse effects. Iobitridol is generally well tolerated. The only side effect observed in more than 1% of patients is nausea. Rare side effects (in fewer than 1 per 10.000 people) include anaphylaxis (severe allergic reactions), circulatory collapse, kidney failure, thyroid-related effects, and skin reactions such as Stevens–Johnson syndrome.
Side effects may include allergic reactions, headache, vomiting, and conjunctivitis. Long term use may result in trouble sleeping and depression. It should not typically be used during pregnancy or breastfeeding. Lugol's iodine is a liquid made up of two parts potassium iodide for every one part elemental iodine in water.
Excess iodine consumption notably from algae such as kelp. Thyrotoxicosis can also occur after taking too much thyroid hormone in the form of supplements, such as levothyroxine (a phenomenon known as exogenous thyrotoxicosis, alimentary thyrotoxicosis, or occult factitial thyrotoxicosis).
Side effects include skin irritation and sometimes swelling. If used on large wounds, kidney problems, high blood sodium, and metabolic acidosis may occur. It is not recommended in women who are less than 32 weeks pregnant. Frequent use is not recommended in people with thyroid problems or who are taking lithium.
Iodine. Guidelines recommend the administration of inorganic iodide (potassium iodide or Lugol's iodine) to reduce the synthesis and release of thyroid hormone. In high dosage, iodine may reduce the synthesis of thyroid hormone via the Wolff–Chaikoff effect and its release via the Plummer effect.
The incidence of life-threatening hypersensitivity reactions occurring during surgery and anesthesia is around one in 10,000 procedures. [1] Serious allergic reactions to anesthetic medications are rare and a usually attributable to factors other than the anesthetic.
The adverse effects of radiocontrast can be subdivided into type A reactions (e.g. thyrotoxicosis), and type B reactions (hypersensitivity reactions: allergy and non-allergy reactions [formerly called 'anaphylactoid reactions']).