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CLL/SLL MBL consist of two groups: low-count CLL/SLL MBL has monoclonal B-cell blood counts of <0.5x 9 cells/liter (i.e. 0.5x 9 /L) while high-count CLL/SLL MBL has blood monoclonal B-cell counts ≥0.5x 9 /L but <5x10 9 /L. Individuals with blood counts of these monoclonal B-cells >5x 9 /L are diagnosed as having CLL. Low-count CLL/SLL MBL ...
Leukemia ( also spelled leukaemia and pronounced / luːˈkiːmiːə / [1] loo-KEE-mee-ə) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. [9] These blood cells are not fully developed and are called blasts or leukemia cells. [2]
Hematology. In medicine ( hematology ), bleeding diathesis is an unusual susceptibility to bleed ( hemorrhage) mostly due to hypocoagulability (a condition of irregular and slow blood clotting), in turn caused by a coagulopathy (a defect in the system of coagulation ). Therefore, this may result in the reduction of platelets being produced and ...
Leukostasis, also known as symptomatic hyperleukocytosis, is a life-threatening complication of various leukemias characterized by an excess of white blood cells in the bloodstream. Hyperleukocytosis is arbitrarily defined as greater than 100,000 white blood cells per microliter of blood.
Giant platelet disorders, also known as macrothrombocytopenia, are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency to bleeding. Giant platelets cannot stick adequately to injured blood vessel walls, resulting in abnormal bleeding when injured.
When a child has leukemia, the cells do not respond to the signals telling them when to stop and when to produce cells. The bone marrow becomes crowded, resulting in problems producing other blood cells. Common childhood leukemia signs and symptoms include excessive tiredness, easy bruising or bleeding, bone pain and paleness.
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