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  2. Sofía Jirau - Wikipedia

    en.wikipedia.org/wiki/Sofía_Jirau

    Sofía Isabel Jirau González (born March 26, 1997) is a Puerto Rican model with Down syndrome. Personal life. Jirau was born in Puerto Rico to Frankie Jirau and Mimi González. She is the second eldest of four children.

  3. Down syndrome - Wikipedia

    en.wikipedia.org/wiki/Down_syndrome

    Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] It is usually associated with developmental delays, mild to moderate intellectual disability, and characteristic physical features. [1] [12] There are three types of Down syndrome, the ...

  4. Down syndrome research - Wikipedia

    en.wikipedia.org/wiki/Down_syndrome_research

    Down syndrome research. Research of Down syndrome-related genes is based on studying the genes located on chromosome 21. In general, this leads to an overexpression of the genes. [1] [2] Understanding the genes involved may help to target medical treatment to individuals with Down syndrome. It is estimated that chromosome 21 contains 200 to 250 ...

  5. List of people with Down syndrome - Wikipedia

    en.wikipedia.org/wiki/List_of_people_with_Down...

    The average IQ of a young adult with Down syndrome is 50, equivalent to the mental age of an 8- or 9-year-old child, but this number varies widely. At the same time, they enjoy a rich social and emotional awareness. Down syndrome is the most common chromosome abnormality in humans, occurring in about one per 1000 babies born each year.

  6. Down by the Riverside - Wikipedia

    en.wikipedia.org/wiki/Down_by_the_Riverside

    Down by the Riverside" (also known as "Ain't Gonna Study War No More" and "Gonna lay down my burden") is an African-American spiritual. Its roots date back to before the American Civil War , [1] though it was first published in 1918 in Plantation Melodies: A Collection of Modern, Popular and Old-time Negro-Songs of the Southland , Chicago, the ...

  7. System of a Down discography - Wikipedia

    en.wikipedia.org/wiki/System_of_a_Down_discography

    System of a Down is an American heavy metal band formed by vocalist Serj Tankian, guitarist Daron Malakian, bassist Shavo Odadjian, and drummer John Dolmayan in the mid-1990s. They have released five studio albums, nineteen singles (including promotional releases), and thirteen music videos. By the end of 1997, the group had signed to American ...

  8. Up the Down Staircase (film) - Wikipedia

    en.wikipedia.org/wiki/Up_the_Down_Staircase_(film)

    Up the Down Staircase is a 1967 American drama film directed by Robert Mulligan and starring Oscar winners Sandy Dennis and Eileen Heckart, along with Patrick Bedford and Jean Stapleton. The plot concerns the first, trying assignment for a young, idealistic teacher. Tad Mosel wrote the screenplay adaptation of the novel of the same name by Bel ...

  9. Lie Down in Darkness (novel) - Wikipedia

    en.wikipedia.org/wiki/Lie_Down_In_Darkness_(novel)

    Lie Down in Darkness is the first novel by American novelist William Styron, published in 1951. Written when he was 26 years old, the novel received a great deal of critical acclaim. After graduating from Duke University in 1947, Styron took an editing position with McGraw-Hill in New York City. After provoking his employers into firing him, he ...

  10. Gray Lady Down - Wikipedia

    en.wikipedia.org/wiki/Gray_Lady_Down

    Gray Lady Down. Gray Lady Down is a 1978 American submarine disaster film directed by David Greene and starring Charlton Heston, David Carradine, Stacy Keach, Ned Beatty, Ronny Cox and Rosemary Forsyth, and includes the feature film debut of Michael O'Keefe and Christopher Reeve. It is based on David Lavallee's 1971 novel Event 1000.

  11. Black Hawk Down (soundtrack) - Wikipedia

    en.wikipedia.org/wiki/Black_Hawk_Down_(soundtrack)

    Black Hawk Down is the soundtrack accompanying the 2001 film of the same name.The original score was composed by Hans Zimmer.The music was written in collaboration with several other musicians (including Martin Tillmann, Craig Eastman, Michael Brook, Heitor Pereira and Mel Wesson) in what was referred to as "The War Room" at the Media Ventures studios.