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Stem cells have been used to repair tissue damaged by disease or age. [2] Cloning also might be done with stem cells. Pluripotent stem cells can also be derived from Somatic cell nuclear transfer which is a laboratory technique where a clone embryo is created from a donor nucleus.
Deeper into Stem cell therapy is multipotent cell introduction. The multipotent cell is a less specified bone stem cell and the theory is that the cells can turn into not only bone but other tissue cell types that will increase the repair of the femoral head as a whole when used alongside vascularized bone grafts.
The morphology and growth factors of these lab induced pluripotent cells, are equivalent to embryonic stem cells, leading these cells to be known as induced pluripotent stem cells (iPS cells). [75] This observation was observed in mouse pluripotent stem cells, originally, but now can be performed in human adult fibroblasts using the same four ...
Gene therapy for osteoarthritis is the application of gene therapy to treat osteoarthritis (OA). Unlike pharmacological treatments which are administered locally or systemically as a series of interventions, gene therapy aims to establish sustained therapeutic effect after a single, local injection.
Organoids are derived from three kinds of human or animal stem cells—embryonic pluripotent stem cells (ESCs), adult somatic stem cells (ASCs), and induced pluripotent stem cells (iPSCs). These organoids are grown in vitro and mimic the structure and function of different organs such as the brain, liver, lung, kidney, and intestine. Organoids ...
Renal cells and nephrons have already been simulated by microfluidic devices. "Such cell cultures can lead to new insights into cell and organ function and be used for drug screening". [56] A kidney-on-a-chip device has the potential to accelerate research encompassing artificial replacement for lost kidney function.
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