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Knuckle pads are benign subcutaneous fibrotic nodules that are seen in the finger joints and/or the extensor area of the foot. [6] [7] [8] From a clinical perspective, these are well-defined, non-compressible, freely moveable lesions that resemble warts and primarily affect the dorsal portion of the proximal interphalangeal (PIP) and, less frequently, the metacarpophalangeal (MCP) joints.
There are also a number of other conditions that affect hands, feet, and parts of the face with associated skin color changes that need to be differentiated from acrocyanosis: Raynaud phenomenon, pernio, acrorygosis, erythromelalgia, and blue finger syndrome. The diagnosis may be challenging in some cases, especially when these syndromes co-exist.
The condition generally arises from the patient's knuckles making contact with the incisor teeth during the act of inducing the gag reflex at the back of the throat with their finger(s). [ 3 ] This type of scarring is considered one of the physical indicators of a mental illness , and Russell's sign is primarily found in patients with an eating ...
A chastity device designed to be fastened around the penis and cause pain if it becomes erect. Cock and ball torture (CBT) [a] is a sexual activity involving the application of pain or constriction to the male genitals.
Five Finger Death Punch, also abbreviated as 5FDP or FFDP, is an American heavy metal band from Las Vegas, Nevada, formed in 2005.The band originally consisted of vocalist and keyboardist Ivan Moody, rhythm guitarist Zoltan Bathory, lead guitarist Caleb Andrew Bingham, bassist Matt Snell, and drummer Jeremy Spencer.
Gout (/ ɡ aʊ t / GOWT [9]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [4] [10] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [11] Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. [7]
Zinc fingers were first identified in a study of transcription in the African clawed frog, Xenopus laevis in the laboratory of Aaron Klug.A study of the transcription of a particular RNA sequence revealed that the binding strength of a small transcription factor (transcription factor IIIA; TFIIIA) was due to the presence of zinc-coordinating finger-like structures. [6]
Cat bites are bites inflicted upon humans, other cats, and other animals by the domestic cat (Latin: Felis catus). [1] [2] Data from the United States show that cat bites represent between 5–15% of all animal bites inflicted to humans, [3] [4] but it has been argued that this figure could be the consequence of under-reporting as bites made by cats are considered by some to be unimportant.
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