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Recent research demonstrates that articular cartilage may be able to be repaired via the percutaneous introduction of mesenchymal stem cells (MSC's). Stem cells, as a concept, originated as a theory in the 19th century to potentially allow certain tissues to self-renew.
Hip replacement is one of the most common orthopaedic operations, though patient satisfaction varies widely. Approximately 58% of total hip replacements are estimated to last 25 years. The average cost of a total hip replacement in 2012 was $40,364 in the United States, and about $7,700 to $12,000 in most European countries.
Costs of stem cell therapies range widely by clinic, condition, and cell type, but most commonly range between $10,000-$20,000. Insurance does not cover stem cell injections at clinics so patients often use on-line fundraising.
An advantage to this approach is that a person's own stem cells are used, avoiding tissue rejection by the immune system. Stem cells enable surgeons to grow replacement cartilage, which gives the new tissue greater growth potential.
Blood and bone marrow (which contains stem cells) seep out of the fractures, creating a blood clot that releases cartilage-building cells. The microfractures are treated as an injury by the body, which is why the surgery results in new, replacement cartilage.
A colony of human embryonic stem cells. Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function".
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