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Sofía Isabel Jirau González (born March 26, 1997) is a Puerto Rican model with Down syndrome. Personal life. Jirau was born in Puerto Rico to Frankie Jirau and Mimi González. She is the second eldest of four children.
Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] It is usually associated with developmental delays, mild to moderate intellectual disability, and characteristic physical features. [1] [12] There are three types of Down syndrome, the ...
World Down Syndrome Day ( WDSD) is marked each year on March 21, [1] beginning in 2007. The 21st day of March (the 3rd month of the year) was selected to signify the uniqueness of the triplication ( trisomy) of the 21st chromosome which causes Down syndrome. The General Assembly of the United Nations has decided to observe it each year since 2012.
Genetics of Down syndrome. Down syndrome is a chromosomal abnormality characterized by the presence of an extra copy of genetic material on chromosome 21, either in whole ( trisomy 21) or part (such as due to translocations ). The effects of the extra copy varies greatly from individual to individual, depending on the extent of the extra copy ...
John Langdon Down. John Langdon Haydon Down (18 November 1828 – 7 October 1896) was a British physician best known for his description of the genetic condition now known as Down syndrome, which he originally classified in 1862. He is also noted for his work in social medicine and as a pioneer in the care of mentally disabled patients.
Down syndrome research. Research of Down syndrome-related genes is based on studying the genes located on chromosome 21. In general, this leads to an overexpression of the genes. [1] [2] Understanding the genes involved may help to target medical treatment to individuals with Down syndrome. It is estimated that chromosome 21 contains 200 to 250 ...
The average IQ of a young adult with Down syndrome is 50, equivalent to the mental age of an 8- or 9-year-old child, but this number varies widely. At the same time, they enjoy a rich social and emotional awareness. Down syndrome is the most common chromosome abnormality in humans, occurring in about one per 1000 babies born each year.
Box office. $62.1 million [2] Down and Out in Beverly Hills is a 1986 American comedy film based on the 1919 French play Boudu sauvé des eaux, which was later adapted as Boudu sauvé des eaux, a 1932 film by Jean Renoir. Down and Out in Beverly Hills was directed by Paul Mazursky, and starred Nick Nolte, Bette Midler and Richard Dreyfuss. [3]
Down in Mississippi (Up to No Good) "Down in Mississippi (Up to No Good)" is a song written and recorded by American country music group Sugarland. It was released in March 2006 as the fourth and final single from the album Twice the Speed of Life, Sugarland's only album as a trio. Starting with the next single, "Want To", Sugarland has ...
"Down" is a song by American electronic duo Marian Hill as a single from their debut album Act One. Originally released in 2016, the song became popular after its adoption by Apple in an AirPods commercial. The song started to gain more traction over the following weeks, debuting on the Billboard Hot 100 and Alternative Songs chart.