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Risk factors include having a family history of the disease, with 10% of those who develop CLL having such ancestry. [2] [9] Exposure to Agent Orange , certain insecticides , sun exposure , exposure to hepatitis C virus , and common infections are also considered risk factors.
Chronic lymphocytic leukemia (CLL) most often affects adults over the age of 55. It sometimes occurs in younger adults, but it almost never affects children. Two-thirds of affected people are men. The five-year survival rate is 85%. It is incurable, but there are many effective treatments.
Poor. Frequency. rare. Richter's transformation (RT), also known as Richter's syndrome, is the conversion of chronic lymphocytic leukemia (CLL) or its variant, small lymphocytic lymphoma (SLL), into a new and more aggressively malignant disease. [1] CLL is the circulation of malignant B lymphocytes with or without the infiltration of these ...
May progress to chronic lymphocytic leukemia or certain lymphoma types; increased risk of developing non-hematologic cancers, serious infections, and kidney disease: Duration: chronic: Types: CLL/SLL, atypical CLL/SLL, non-CLL/SLL, and MBL-MZ
Risk factors Genetics. Common inherited risk factors include mutations in ARID5B, CDKN2A/2B, CEBPE, IKZF1, GATA3, PIP4K2A and, more rarely, TP53. These genes play important roles in cellular development, proliferation, and differentiation. Individually, most of these mutations are low risk for ALL. Significant risk of disease occurs when a ...
B-cell leukemia; T-cell leukemia; NK-cell leukemia; The most common type of lymphoid leukemia is B-cell chronic lymphocytic leukemia. B-cell leukemias. B-cell leukemia describes several different types of lymphoid leukemia which affect B cells.
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