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Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
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In people with GHRH-producing, non-pituitary tumors, the pituitary still may be enlarged and may be mistaken for a tumor. Therefore, it is important that physicians carefully analyze all "pituitary tumors" removed from people with acromegaly so as to not overlook the possibility that a tumor elsewhere in the body is causing the disorder.
Treatment of macroorchidism depends on pathogenesis. Surgical removal of the tumor is the most important and advised option for treating macroorchidism caused by non-functioning pituitary macroadenoma. [12] A non-functioning pituitary adenoma is a kind of benign tumor that does not secrete active hormones, and is from the pituitary gland. [13]
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Since pharmacological therapy has had little effect on these tumors, a trans-sphenoidal surgery to remove part of the pituitary gland is the first treatment option. [ 5 ] TSH-secreting : Another rare condition only resulting in 1% of pituitary surgeries is a result of the increase in the secretion of the thyroid-stimulating hormone .
The treatment requires frequent monitoring to the 1 in 30,000 that suffer from MEN-1. [3] Endocrine pancreatic tumor are treated with surgery and cytotoxic drugs in case of malignant disease. Pituitary tumors are treated with surgery (acromegaly and Mb. Cushing) or medicine (prolactinomas). [3]
A pituitary tumor causes SUNCT as a secondary headache. Some patients with a pituitary tumor complain of short-lasting heachaches. Upon removal of the tumor, the symptoms of SUNCT may disappear permanently. [11] Although it occurs very rarely, paranasal sinusitis can also cause secondary SUNCT. The symptoms of SUNCT in such cases can be removed ...