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Vitiligo ( / ˌvɪtɪˈlaɪɡoʊ /) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [5] [6] Treatment options include topical medications, light therapy, surgery and cosmetics. [6]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system —the organ system that encloses the body and includes skin, nails, and related muscle and glands. [1] The major function of this system is as a barrier against the external environment. [2]
Schamberg's disease, or progressive pigmented purpuric dermatosis, is a chronic discoloration of the skin which usually affects the legs and often spreads slowly. This disease is more common in males and may occur at any age from childhood onward. This condition is observed worldwide and has nothing to do with race or ethnic background.
Health and appearance of Michael Jackson. Michael Jackson in 1977 at age 18 (left) and 1997 at age 38 (right) Michael Jackson was an American entertainer who spent over four decades in the public eye, first as a child star with the Jackson 5 and later as a solo artist. From the mid-1980s, Jackson's appearance began to change dramatically.
The condition is the most severe form of ichthyosis (except for syndromes that include ichthyosis, for example, Neu–Laxova syndrome), a group of genetic disorders characterised by scaly skin. [8] Harlequin-type ichthyosis is caused by mutations in the ABCA12 gene . [4]
Ichthyosis (also named fish scale disease) [1] is a family of genetic skin disorders characterized by dry, thickened, scaly skin. [2] The more than 20 types of ichthyosis range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., dominant, recessive, autosomal or X-linked ). [3]
Hailey–Hailey disease (HHD), or familial benign chronic pemphigus: 559 or familial benign pemphigus,: 622 was originally described by the Hailey brothers (Hugh Edward and William Howard) in 1939. [3] [4] It is a genetic disorder that causes blisters to form on the skin.
Stevens–Johnson syndrome ( SJS) is a type of severe skin reaction. [1] Together with toxic epidermal necrolysis (TEN) and Stevens–Johnson/toxic epidermal necrolysis (SJS/TEN) overlap, they are considered febrile mucocutaneous drug reactions and probably part of the same spectrum of disease, with SJS being less severe.
Epidermodysplasia verruciformis. Epidermodysplasia verruciformis ( EV) is a skin condition characterised by warty skin lesions. [1] It results from an abnormal susceptibility to HPV infection (HPV) and is associated with a high lifetime risk of squamous cell carcinomas in skin. [1] It generally presents with scaly spots and small bumps ...
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