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Lean or purple drank (known by numerous local and street names) is a polysubstance drink used as a recreational drug. It is prepared by mixing prescription-grade cough or cold syrup containing an opioid drug and an anti-histamine drug with a soft drink and sometimes hard candy.
Dexamyl (or Drinamyl in the UK) was a brand name combination drug composed of sodium amobarbital (previously called amylbarbitone and its brand name Amytal) and dextroamphetamine sulfate (Dexedrine) within the same pill. It was widely abused, and is no longer manufactured.
Many rock and roll bands have named themselves after amphetamine and the drug slang and drug culture surrounding it. For example, Mod revivalists The Purple Hearts named themselves after the amphetamine tablets popular with mods during the 1960s, as did the Australian band of the same name during the mid-1960s.
Purple urine bag syndrome ( PUBS) is a medical syndrome where purple discoloration of urine occurs in people with urinary catheters and co-existent urinary tract infection. Bacteria in the urine produce the enzyme indoxyl sulfatase.
A spoonful of promethazine / codeine cough syrup showing the characteristic purple color that gave rise to the name purple drank. Polysubstance use or poly drug use refers to the use of combined psychoactive substances.
In the mid-1990s, it was reported to be a popular street drug among Zambian youth, created by placing feces and urine in a bottle or a bucket, sealing it with a balloon or lid respectively and leaving it to ferment in the sun; afterwards they would inhale the gases generated.
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription.
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The availability of psilocybin mushrooms from wild and cultivated sources has made them one of the most widely used psychedelic drugs. At present, psilocybin mushroom use has been reported among some groups spanning from central Mexico to Oaxaca, including groups of Nahua, Mixtecs, Mixe, Mazatecs, Zapotecs, and others.
There are five major categories for synthetic cannabinoids: classical cannabinoids, non-classical cannabinoids, hybrid cannabinoids, aminoalkylindoles, and eicosanoids. Classical cannabinoids are analogs of THC that are based on a dibenzopyran ring.