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Ocular hypertension. Ocular hypertension is the presence of elevated fluid pressure inside the eye ( intraocular pressure ), usually with no optic nerve damage or visual field loss. [1] [2] For most individuals, the normal range of intraocular pressure is between 10 mmHg and 21 mmHg.
Intraocular pressure ( IOP) is the fluid pressure inside the eye. Tonometry is the method eye care professionals use to determine this. IOP is an important aspect in the evaluation of patients at risk of glaucoma. [1] Most tonometers are calibrated to measure pressure in millimeters of mercury ( mmHg ).
A major risk factor for glaucoma is increased pressure within the eye, known as intraocular pressure (IOP). [1] It is associated with old age, a family history of glaucoma, and certain medical conditions or medications. [6]
The incidence of pigmentary glaucoma decreases with age while in exfoliation syndrome the incidence increases with age. [2] However, given the derived nature of secondary glaucoma, there may be no significant association between age, ethnicity or gender and the prevalence of the condition.
The normal cup-to-disc ratio is less than 0.5. A large cup-to-disc ratio may imply glaucoma or other pathology. [3] However, cupping by itself is not indicative of glaucoma. Rather, it is an increase in cupping as the patient ages that is an indicator for glaucoma. Deep but stable cupping can occur due to hereditary factors without glaucoma.
In people with ocular hypertension (IOP ≥21 mm Hg) including open-angle glaucoma, treatment with latanoprost reduced IOP levels by 22 to 39% over 1 to 12 months’ treatment. Latanoprost is more effective than timolol 0.5% twice daily in 3 of 4 large (n = 163 to 267) randomised, double-blind trials.
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