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  2. Speedball (drug) - Wikipedia

    en.wikipedia.org/wiki/Speedball_(drug)

    Speedballs often give stronger effects than either drug when taken alone due to drug synergy, and are a particularly hazardous mixture that can easily cause heart attack, respiratory arrest and death. [3] When compared to single drugs, speedballs are more likely to lead to addiction, [4] [5] and users are more likely to relapse [4] [6] and also ...

  3. Topiramate - Wikipedia

    en.wikipedia.org/wiki/Topiramate

    Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. [9] It has also been used in alcohol dependence and essential tremor. [9] For epilepsy this includes treatment for generalized or focal seizures. [10] It is taken orally (by mouth). [9]

  4. Adderall - Wikipedia

    en.wikipedia.org/wiki/Adderall

    Adderall and Mydayis [10] are trade names [note 2] for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [12]

  5. Lean (drug) - Wikipedia

    en.wikipedia.org/wiki/Lean_(drug)

    Lean or purple drank (known by numerous local and street names) is a polysubstance drink used as a recreational drug.It is prepared by mixing prescription-grade cough or cold syrup containing an opioid drug and an anti-histamine drug with a soft drink and sometimes hard candy.

  6. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Metformin also interacts with anticholinergic medications, due to their effect on gastric motility. Anticholinergic drugs reduce gastric motility, prolonging the time drugs spend in the gastrointestinal tract. This impairment may lead to more metformin being absorbed than without the presence of an anticholinergic drug, thereby increasing the ...

  7. Congenital insensitivity to pain with anhidrosis - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder of the nervous system which prevents the feeling of pain or temperature and prevents a person from sweating.

  8. Oxycodone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone

    Oxycodone is a Class A drug under the Misuse of Drugs Act 1971. [166] For Class A drugs, which are "considered to be the most likely to cause harm", possession without a prescription is punishable by up to seven years in prison, an unlimited fine, or both. [167]

  9. Amphetamine - Wikipedia

    en.wikipedia.org/wiki/Amphetamine

    Amphetamine is a weak base with a pK a of 9.9; [3] consequently, when the pH is basic, more of the drug is in its lipid soluble free base form, and more is absorbed through the lipid-rich cell membranes of the gut epithelium. [3] [29] Conversely, an acidic pH means the drug is predominantly in a water-soluble cationic (salt) form, and less is ...

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